Methods: Ciprofloxacin was administered to newly born Wistar albino rat pups at a dose of 20 mg/kg body weight intraperitoneally twice daily from day-1 to day-14 after birth. The animals were housed with free access to food and water for one week in an air-conditioned room (250C) under a 12 hr light: dark cycle prior to the experiment. Animal‐rearing facility conditions were optimized for the light–dark cycle, that is, twelve‐hour … Pharm. The number of spike-wave discharges (SWDs) was gradually elevated from the 19th pregnancy day to delivery. This particular colony was selected because of a low incidence of hydronephrosis. To Scientific Products Farm, Ltd. [predecessor of Charles River United Kingdom (CRUK)] in 1947 from Wistar Institute. Eur Rev Med Pharmacol Sci Year: 2020 Vol. Experimental animals: Wistar albino rats were obtained from a Veterinary Stock in Ibadan, Nigeria. Twenty male albino Wistar rats were procured from the laboratory animal‐rearing facility of the faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan. To Charles River in 1975 from CRUK. Lobund-Wistar rat… Methods: 18 male Wistar albino rats were divided into 3 groups with 6 animals in each group. Group 2 and 3 received 0.5 ml of a concoction of Andrographis paniculata and Nilavembu kudineer (a concoction of 9 herbs) respectively for 30 days. The present work investigated the protective effects of Costus afer Ker Gawl. aqueous leaf extract (CALE) on lipid profile and hematological changes induced by exposure to low-dose heavy metal mixture in male albino rats. Male Wistar albino rats (200–250g) were purchased at Albino Research Center, Bachupally, Hyderabad. A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. Cardiovascular System of Albino Wistar Rats Brenno Marco De Russi1 Camila Albuquerque Melo Carvalho1 1Centro Universitário Barão de Mauá, Ribeirão Preto, SP, Brazil J Morphol Sci 2019;36:317–320. Male and female wistar albino rats weighing 150-180 grams, were obtained from the animal house of Sainath Agen-cies, Hyderabad (282/PO/Bt/S/2000 CPCSEA). They were accomodatedin polypropylene cages with standard diet and water ad libitum. BOOT, J. V. CLARKE, and A. Figure 6. A total of 34 male Albino rats [Wistar strain], 2 months of age, weighing 150-160 gm were used for the experiment. Res., 2015, 7(8):729-734 _____ 731 were performed according to the Guide for the care and use of laboratory … Group 2 was exposed to SA at a dose of 4.1 mg/kg body weight (kgbw) for two weeks. They were maintained on a 12-h light-dark cycle in a temperature-controlled (22°C) colony room and had free access to food and water. Wistar albino rats (150-250 g body weight) were used after an acclimatization period of 7 days to the laboratory environment. Wistar IGS Rat Details. Sprague-Dawley rats were derived from Wistar rat. ABSTRACT: Introduction: Global warming is one of the major issues in the … Glory Josephine I. et al J. Chem. Department of Physiology, Meenakshi Medical College & Research Institute, Enathur, Kanchipuram - 631552, Tamil Nadu, India. 24 - N. 22 Pages: 11871-11882 DOI: 10.26355/eurrev_202011_23845. Address for correspondenceCamila Albuquerque Melo de Carvalho, PhD, Centro Universitário Barão de Mauá, Rua Ramos de Azevedo, 423, Ribeirão Preto, SP, 14090 … 12:29. doi: 10.3389/fnbeh.2018.00029 [ Wistar Institute] The rats were maintained in the animal house of Department of Biochemistry, Ahmadu Bello University, Zaria, Nigeria with protocol for the study approved by … Citation: Kovács Z, D'Agostino DP and Ari C (2018) Anxiolytic Effect of Exogenous Ketone Supplementation Is Abolished by Adenosine A1 Receptor Inhibition in Wistar Albino Glaxo/Rijswijk Rats. Wistar Albino Glaxo Rijswijk (WAG/Rij) rats were used in the study as a model of absence epilepsy and because their seizures do not interfere with rearing offspring. Our institutional and national guidelines were followed for the care and use of laboratory animals throughout the experiment. The rats were inflicted with excision wounds as … In phase one, doses of 10, 100 and 1000 mg/kg body weight of rats was administered while in phase two, 1500, 3000 and 5000mg/kg body weight of rats was orally administered. 1, Jan 2013 29 Zahra Bathaie et al Saffron … Wistar rats encompass a number of rat substrains that have been derived from a common lineage over the past 50+ years. Description Price Currency; 50-74g weight, 21-26 approx days: 28.25: USD: 75-99g weight, 27-30 approx days In addition, groups 3 and 4 received 100mg/kg and 150mg/kg oral administration of vitamin C … We tested exogenous ketone supplements added to food and fed chronically for 83 days in SPD rats … During the experimental study rats were fed with … The substrains of Wistar rats: Wistar Hannover (Han/Wistart) and Wistar Unilever (WU) rat are outbred; while Wistar Kyoto and Wistar Furth are inbred strains. This has markedly diluted the original strain. They were allowed to adapt for one week under standard laboratory conditions of 12-hour light-dark cycle before commencement of all experiments. Fresh leaves were shade … Behavioral changes, signs of … The extract administration was in two phases. CARVER University of Sydney, Sydney, Australia Albino and hooded WlStar rats of both sexes were compared on several behavioral measures and learning tasks. The experimental animals were divided into six weight matched groups. They were adequately fed with normal rat chow … Wistar rats: ( wis'tehr ), an inbred strain of rats, homozygous at most loci, produced by strict brother-sister inbreeding over many generations to develop animals for research with the same general genetic composition. 16, No. The first group containing 6 rats was assigned as a control group. Groups 3-11 were treated with ELEIG with or without SA. These animals were killed by deep ether anaesthesia and fixed in 80% alcohol. There are various routes of drug administration in rats like 1) Intraoeritoneal 2) Intravenous3) Intramuscular 4) Subcutaneous 5) Intracardiac etc. Group 1 (control) was given feed and water ad libitum. In order to establish the safety use of TR-Y017, this study aims to evaluate the effects of its acute and sub-acute oral administration to Wistar albino rats. of rats in the USA. Keywords Related articles: The effect of pioglitazone on the liver of streptozotocin-induced diabetic albino wistar rats ; The effects of … Effects and formulation of silver nanoscaffolds on cytotoxicity dependent ion release kinetics towards enhanced excision wound healing patterns in Wistar albino rats L. Sethuram, J. Thomas, A. Mukherjee and N. Chandrasekaran, RSC Adv. Extraction . A. Madhuri *, S. Qairunnisa, M. Suresh, K. Ambareesha Kondam and M. Chandrasekhar. IGS refers to animals bred using the Charles River International Genetic Standardization (IGS) Program. They were provided with food and water ad libitum. ANTIOXIDANT CHANGES IN WISTAR ALBINO RATS AFTER ACUTE HEAT STRESS. Treatment was done orally and lasted for 14 days. Wistar albino rats of weights between 100 and 161 g were assigned to eleven (11) groups of five (5) animals each. Group 1 served as control and received distilled water. Outbred Rats - Hsd:WI - 001. Wistar albino rats. The second group containing 14 rats was exposed to mobile phone radiation for 30 minutes daily and the third group containing 14 rats was exposed to … Lorke’s method was adopted for the determination of the LD 50 of the crude methanol leaf extract of plant. Twenty albino wistar rats were randomly divided into four experimental groups of five rats each, Control group were fed normal rat feed with distilled water, Group 2,3 and 4 were fed normal rat feed, water and received daily oral administration of lead acetate 250mg/kg daily. In addition, Group C and Group D animals were treated with oral administration of 20% and 40% aqueous extract of … This video describes the standard method of collection of blood from retro orbital plexus in wistar albino rats. Twenty female Wistar albino rats, weighing between 160 and 170 g were collected from animal house of Jahangirnagar University, Dhaka and were allowed free access to laboratory rodent diet and water ad-libitum throughout the experimental period. Group A (n=10) was the control group while group B (n=40) was the experimental group. The average weight of randomly selected male rats was in the range between 120 and 130 g in all groups. Rederived by GlaxoWellcome from Han Wistar stock supplied by BRL. Behav. B. Furthermore, B exhibited antioxidant and anti-inflammatory effects and regulated metabolic and histopathological alterations in male Wistar albino rats exposed to BPA. The work was carried out in CPCSEA approved (743/03/ abc/CPCSEA dt. The wistar albino rats were housed in groups of four polycarbonate cages. (20) male albino rats of Wistar (150-195 g) were used in the present study. , 2019, 9 , 35677 The animals were housed in cages kept in an adequate animal house environment at the Madonna University, Elele, Nigeria. Group A Iran J Basic Med Sci, Vol. Finally they were cleared in 4% KOH and stored in glycerin. An authoritative source for the science and technological discoveries that matter for the general public. The outbred Wistar and Wistar HAN strains have been used widely in Europe for … Transferred to Charles River in 1997 and rederived into isolator maintained Foundation Colony. Animal study was performed according to the following process: 50 male Albino Wistar rats, weighing 100-120 grams, after 10 days of acclimatization, the rats were randomly divided into two main groups. The Wistar rat, Wistar Hannover (Wistar HAN) rat, and Wistar Unilever (WU) rat are outbred rat strains, while the Wistar Kyoto and Wistar Furth rats are inbred strains. Nutritional ketosis has been proven effective for seizure disorders and other neurological disorders. Methods: Acute oral toxicity tests were performed on Wistar rats by oral forcefeeding with a single dose of 2000 mg/kg in accordance with the Organization for Economic Co-operation and Development (OECD) Guidelines and … Wistar rat is another common hybrid albino model animal. The normal (group 1) and toxic (group 2) controls received deionized water and metal … He later established Wistar Institute in Philadelphia that will have a major role in the development of the rat as an important laboratory animal similar to the impact the Jackson laboratory had on the development of the laboratory mouse. These animals were divided into 3 groups. Animal Grouping: The study was performed on twenty-four (24) wistar-rmale albino rats housed in ventilated cages and grouped into four of six rats each. The experiments . Keywords: exogenous ketone supplement, ketosis, anxiety, EPM, adenosine, WAG/Rij rats. Transferred to Charles River UK in 1996. They were then bulk stained with Alizarin red and Alcian blue. Overall the most marked behavioral differences produced by … The animals were allowed to acclimatize for seven days before the commencement of administration. However, B administration reversed BPA-induced alterations in rat tissues in a dose-dependent manner. Meanwhile, the characteristics of individual SWDs did not change suggesting that SWD … Groups B, C and D were administered 30mg/kg body weight potassium bromate. Neurosci. Serum … Excision Wound . The focus of this study was to determine the effects of ketone supplementation on anxiety-related behavior in Sprague-Dawley (SPD) and Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats. The experimental protocols followed were in accordance with the NIH guidelines and approved by the … In order to evaluate the protective effects of Corchorus olitorius leaves, twenty Wistar albino rats were divided into four different groups. Pharmaco-molecular assessment of the effects of anandamide and its antagonists on hippocampal tissue in Wistar albino rats. It has the distinct honor of being the first rat stock developed to serve as a model animal. … 3.3.03) Animal House of PRIST University, Thanjavur. •The Wistar bloodline has contributed more strains of rats than any other line. Front. Wistar albino rats (male), weighing 150 ± 10 g, used for the study, were housed in cage individually under controlled conditions of 12 h light/12 h dark cycle and at a temperature of 22 ± 2°C, with free access to rat/mice feed (Lipton, India) and water ad libitum. Group A served as the control. 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