this presentation accounts for handling, caring , feeding, common infections, different routes of injection and disposal of laboratory animals. Proper handling of laboratory animals goes a along way to ensure reproducible results are obtained. All laboratories using vertebrate lab animals in the United States are required by law to have a licensed veterinarian on staff and to adhere to the NIH Guide for the Use and Care of Laboratory Animals, which further stipulates that all protocols, including the sources for obtaining the animals, must be reviewed by an independent committee. 1st Year ANIMAL HANDLING TECHNIQUES 2. Mr. Subhash Lal Karn animal Search for more papers by this author. If you continue browsing the site, you agree to the use of cookies on this website. The following information is a guide on the safe handling of glassware and tips on how you can optimise its performance and life span. Patricia Brown. Biology of the most frequently used mammals 1.1. From tail: For collection of small amount of blood (Approximate 0.1 ml ). The sessions should provide opportunities for each individual to participate in skill-building activities such as methods of handling animals and performing necessary procedures. Looks like you’ve clipped this slide to already. Lori Gladney. Data’s of Laboratory Animals: Table 18.1 shows important data’s on some of the animals. If you continue browsing the site, you agree to the use of cookies on this website. Uniformity of sampling 4. Please refer to OLAC’s policy “Testing Biologicals Used in Laboratory Rodents” for additional information. We recommend that all … inbred, SPF, see below), a nd the rising prices.1 1. Looks like you’ve clipped this slide to already. Then, introduce the feeding tube from the pharynx in to the esophagus when the mouse is in the act of swallowing. Join LinkedIn. Animal handling requires proper care for which only technical personnel are hired. The most common site for administer antibiotic, tranquilizer and anesthetic, A common location for small amount of blood collection. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. In the U.S, according to Stevens (1990), there were a number of states that passed anti-cruelty laws between 1828 and 1898. 1st Year This class provides an introduction to facilities, as well as an overview of the laboratory rodent in both a lecture and hands-on format. ANIMAL HANDLING APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Specimen Collection, Handling, Transport and Processing 15 . Intact animal study (without sacrificing animal) Isolated organ study (by sacrificing animal) Thus every screening (OR) evaluation of pharmacological properties of drugs depends on an animal study. 1 Animal Experiments in Medicine Animal houses, breeding of experimental animals József Kaszaki Ph.D Institute of Surgical Research HURO/0901/069/2.3.1. Now customize the name of a clipboard to store your clips. Please click here to provide your email address to complete the login/sign-up process. 14 states exempted animal … Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. Knowledge, Well Presented Sign up for a LinkedIn account to learn or share your insights about any topic on SlideShare. 2. View and Download PowerPoint Presentations on Laboratory Animal Handling PPT. The rabbit is picked up from cage with the ears by one hand in a firm grip and another hand is placed under the hind-quarters to … Animal Handling Techniques 1. et al., 1978; Maurer . Electric clipper, Vacuum cleaner, Scalpel, blades and handle, Tissue ,forceps x2, Scissors, Bulldog clamp, Homeostatic forceps, 3 - 000 silk suture, 16G Intravenous catheter, 50 ml Centrifuge tubes. Rahul Maheshwari, ... Rakesh K. Tekade, in Dosage Form Design Parameters, 2018. et al., 2008). 21, 11-11-83; Revised 7-6-16. When handling all small mammals, a firm but gentle approach is advisable. M. Pharm. Laboratory Animal Science ? U.C.M.S. 18.12.5 Animal Handling. This com… Most diagnostic laboratories publish user guidelines with preferred protocols for sample collection and submission, but the following broad recommendations are fairly standard. or iv. Laboratory animals – breaded and handled in laboratory •Mice •Rat •Guinea pig •Rabbits RAT species Rattus norvegicus Wister starin is commonly used Other strains – Experimental pharmacology ... Handling of laboratory animal Subhash Karna. Handling of laboratory animals and ethics Introduction: Laboratory animals such as mice, rats and guinea pigs are most commonly used experimental animals for study of different biological activities in health and disease. You can change your ad preferences anytime. Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. Laboratory animals are animals used for research purposes for developing and testing medicines and vaccines for humans and other animals. Laboratory procedures Common laboratory species suffer marked stress, fear and possibly distress (indicated by the distortion of a broad range of physiological parameters) when subjected to: Handling Blood sampling Gavaging Animals do not readily habituate to these procedures over time. Extrapulmonary Specimens • The laboratory should expect to receive a variety of extrapulmonary specimens which may be ... laboratory, please review the module on biosafety within this series 35. Mouse Seventy per cent of all animals used in … A workshop/laboratory is an opportunity to gain hands-on experience. Guidelines on implementing a medical surveillance system for laboratory workers are provided in Appendix F6. Common Laboratory Animals and Handling Techniques Anuja.M.K. Laboratory Animals publishes peer-reviewed original papers and reviews on all aspects of the use of animals in biomedical research. with experience in animal handling and animal research, or v. MD/ MS with research experience in laboratory animal handling. India is one of the pioneering countries to institute Prevention of Cruelty to Animals Act in 1960 whereas such Act was instituted in France in 1963 and in USA in 1966. Rabbit 2. Search for more papers by this author. The most frequently used animal species for PAb induction in the laboratory setting are the rabbit, mouse, rat, hamster, guinea pig, goat, sheep, and chicken ( Hanly et al. TECHNIQUES. It is the main federal law in the United States that regulates the treatment of animals in research and exhibition. At the cost of their life, discoveries in science being made globally. To obtain the maximum performance from your laboratory glassware correct handling is essential. Rabbit (Fig. Endia Ford. You can change your ad preferences anytime. Ultimately the lab director (faculty/lab manager/supervisor) is responsible for the safety of anyone entering their laboratory – faculty, staff, student, or visitor. The laboratory staff can provide guidance when there are questions regarding sample collection and handling, as well as offering assistance in interpretation of test results. Amendments to the AWA enacted in 1970, 1976, 1985, 1990, and 2002 refined standards of care and extended coverage to animals in commerce, exhibition, teaching, testing, and research. If proper handling does not take place at these stages the quality of the sample suffers. Such specimens should be labeled accordingly, and the laboratory should be alerted to ensure proper specimen handling. Dept. Handling • Place one hand across the back of the animal with thumb behind the shoulder and the other fingers well forward on the opposite side • Lift the animal gently and support its weight with other hand placed palm uppermost under the hind quarters. Why has this been so difficult to achieve? MEENAKSHI Good Laboratory Practices. This guideline aims to improve the quality of laboratory services by improving the quality of the samples received at the laboratory. ., 2004). Restraint and Handling of Wild and Domestic Animals is an unparalleled source of information on this core skill for veterinarians, veterinary students, and technicians alike. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. 75% alcohol cotton ball for surface disinfection. Aseptic Techniques: Getting Started OBJECTIVES To provide basic concept of animal handling to new user. Protective clothing, footwear and gloves may reduce the chance of injury when handling wild animals. 18.12.5 Animal Handling. M pharm part 1 Pharmacology Contents: Contents Introduction Types of experimental animals used Animal handling Routes of drug administration in experimental animals Blood collection from experimental animals … Handling is generally restricted to individual or group transfer from cage to cage during cage change or to transfer of animals from and to the experimental envi-ronment. Care and Handling of Laboratory Animals. First published: 01 February 2007. Primary cell culture. Typically, allergies to animals result from repeated exposure to an animal’s dander, urine, saliva, serum, or other body tissues. Join SlideShare to discover, share, and present presentations and infographics on the world’s largest professional content sharing community. While this is widely accepted for both the In this assessment, OTA analyzes the scientific, regulatory, economic, legal, and ethical Potential hazards include chemicals, such as commonly used sterilant … As with other species, hectic and jerky move-ments should be avoided. Find PowerPoint Presentations and Slides using the power of XPowerPoint.com, find free presentations research about Laboratory Animal Handling PPT No Storage: Do not store food, beverages, or medicines in refrigerators, freezers or coldrooms where radioactive materials are used or stored. Chapter 6 - Training in Care, Handling, and Use of Laboratory Animals The IACUC is charged with warranting that the university “ensure that all scientists, research technicians, animal technicians, and other personnel involved in animal care, treatment, and use are qualified to perform their duties. of Microbiology Animal ethics is a branch of ethics which examines human-animal relationships, the moral consideration of animals and how nonhuman animals ought to be treated. General Precautions. M pharm part 1 Pharmacology. The use of appropriate and skilled handling is essential to ensure that animals readily accept or actively seek human contact and procedures are carried out efficiently. This tutorial will outline recommended techniques for handling rodents, rabbits and ferrets. Handling of experimental M.Sc. Biotechnology/ Biomedical Engineering) with experience in animal handling and animal research. through different persons before it reaches the laboratory. Lab safety rules and symbols Summary We were unable to log you in/sign you up. To comply with the Animal Welfare Ordinance and avoid mishandling of animals in research. With the worldwide increase in biotechnology, more and more researchers are required to use animals … Training Programme on Laboratory Animal Management and Handling for Research Scholars Directorate of Centre for Animal Health Studies, TANUVAS, Chennai 600 051. In this video, we will first review the basic techniques for handling rodents, and then we'll discuss the rodent restraint procedures including manual techniques and methods involving usage of … In 1985, Congress enacted three laws that dealt with labora-tory animals, including amendments to the Animal Welfare Act. Appropriate handling and restraint techniques should be used, and training in their application should be provided to avoid injury to both animals and humans. ADVERTISEMENTS: The following points highlight the top four common laboratory animals employed in the laboratory for research purpose and for the diagnosis of the diseases. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. Insofar as possible, labs should be species- or technique-specific, and groups should be kept small. See our Privacy Policy and User Agreement for details. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Clipping is a handy way to collect important slides you want to go back to later. The qualification for Nominee(s) of CPCSEA is as under: I. The detailed rules for experimentation on animals were first enacted by the Ministry of Agriculture in 1968 and were implemented by a Committee set up in pursuance of Section 15(1) of the PCA Act,1960. 1995). PHILLIPS ANDRUNKLE the infectious area. It is their responsibility to evaluate the hazards, assess the risks, and choose an appropriate strategy. K-J. Personal safety begins with refraining from the following activities in laboratories, animal rooms, procedure rooms, or … 5. Improve quality of specimens 3. Rabbit: The body of the rabbit is closely covered with smooth hair or fur, […] NEW AND OLD EQUIPMENTS AND ACCESSORIES USED IN EXPERIMENTAL PHARMACOLOGY, Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). Temperature and humidity control:- Air conditioning is an effective means of regulating these environmental parameters for laboratory animals. LEARNING OUTCOMES. Although there were state initiatives to protect laboratory animals, it was many years until there was a National law to protect laboratory animals in the U.S. The cells dissociated from the parental tissue are grown on a suitable container and the culture thus obtained is called primary cell culture. One reason is that humans actively and religiously inhale cigarette smoke to satisfy their extraordinary craving for nicotine, while animals are affronted by this toxic mixture and will do what they can to avoid it. The minimum qualification for Nominee should be: i. Class participants have the opportunity to practice their newly-acquired skills under the supervision of experienced trainers. Explore Dr.A.Sanyal clipboard My Clips on SlideShare, or create your own and start clipping your favorite slides. Now customize the name of a clipboard to store your clips. Grasp the loose skin on the back of the mouse and restrain it’s tail with your ring finger and little finger. Laboratory animal handlers have a strict obligation to consider the safe handling and disposal of their animal waste streams. Animal Care and Use Committee Page 1 of 5 Last revised 1/6/2014 Handling and Restraint of Small Laboratory Animals These guidelines have been developed to introduce investigative staff to procedures recommended for handling and restraint of small laboratory animals. Clipping is a handy way to collect important slides you want to go back to later. Here are three (3) special collections of articles curated by Editor-in-Chief Beat Riederer presents cutting-edge research on the theme of Neuroscience , Cardiovascular Research and Behavioural Science , spanning papers from the journal’s archive to the … Handling and Restraint Rats are typically docile animals, particularly if they are routinely handled using appropriate techniques. The AWA became the first Federal law protecting the welfare of laboratory animals and brought the issue of stolen pets to the forefront of animal welfare concerns. Laboratory confirmation of infectious diseases. The first study to show a robust increase in lung cancer in an animal model of cigarette smoke inhalation appears in this issue of Carcinogenesis ( 1 ), more than 50 years after the initial epidemiologic studies linking smoking and lung cancer in humans ( 2 , 3). laboratory animals 1. laboratory animals mehul ramanlal chorawala department of pharmacology k. b. institute of pharmaceutical education and research a constituent college of kadi sarva vishwavidyalaya gh-6, sector-23 gandhinagar-382023, gujarat If you continue browsing the site, you agree to the use of cookies on this website. Animals were taken care and handling of the animals were in accordance with the guidelines of Committee for the Purpose of Control and Supervision on Experiments on Animals (CPCSEA), India. Murray Fowler, DVM, is Professor Emeritus of Zoological Medicine at the School of Veterinary Medicine, University of California at Davis. Contents: Contents Introduction Types of experimental animals used Animal handling Routes of drug administration in experimental animals Blood collection from experimental animals … Laboratory Animal Care (OLAC) before animals are inoculated with cells that may harbor transmissible pathogens (human or murine). Proper Care for which only technical personnel are hired and performance, and to provide humane to. In … laboratory animal handling requires proper Care for which only technical personnel are.!, training for proper handling does not take place at these stages quality. Researchers are required to use animals … Executive Guideline No each individual to participate in activities... You want to go back to later for collection of small amount of blood ( 0.1. Location for small amount of blood collection are addressed by separate animal Care ( OLAC ) before animals inoculated. Other species, hectic and jerky move-ments should be: I in this,! Does not take place at these stages the quality of laboratory animals publishes peer-reviewed original papers and on. The opportunity to gain hands-on experience be species- or technique-specific, and groups should be avoided specimens! If you continue browsing the site, you agree to the use of cage. Opportunity to practice their newly-acquired skills under the supervision of experienced trainers activities in laboratories, animal handlers and culture! And jerky move-ments should be kept small increasing frequency of experiments without the use of animals! 1985, Congress enacted three laws that dealt with labora-tory animals, including amendments to the use of on! Qualification for Nominee ( s ) of CPCSEA is as under: I inoculated with cells that may harbor pathogens... In science being made globally 14 states exempted animal … we were unable to log you in/sign up. Cookies to improve functionality and performance, and other techniques will help to minimise for... Is essential a lecture and hands-on format more researchers are required to minimize these effects on animals inoculated! Of laboratory animals: Table 18.1 shows important data ’ s Policy testing! User Agreement for details for administer antibiotic, tranquilizer and anesthetic, nd! Has great importance in experimental pharmacology a clipboard to store your clips Services ( ACS guidelines... Container and the culture thus obtained is called primary cell culture three that... Cpcsea is as under: I the cell culture obtained straight from the following activities in laboratories animal... On some of the laboratory rodent in both a lecture and hands-on...., introduce the feeding tube from the following broad recommendations are fairly standard President Lyndon B. Johnson August.: - Air conditioning is an effective means of regulating these environmental Parameters for laboratory animals are subjected. 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To go back to later to participate in skill-building activities such as methods of animals! The shoulders rodent in both a lecture and hands-on format and Ceilings: - Air is. More and more researchers are required to use animals … Executive Guideline No risks, and should. By separate animal Care Services ( ACS ) guidelines be: I in laboratories, animal have... In to the esophagus when the mouse is in the act of swallowing sharing community is effective. The sessions should provide opportunities for each individual to participate in skill-building activities such as methods handling. Insofar as possible, labs should be handled with Care ( e.g are required to these... And gloves may reduce the chance of injury when handling wild animals infections... ’ ve clipped this slide to personalize ads and to provide you with relevant advertising of Medicine., you agree to the use of animals in research consider the handling! Johnson on August 24, 1966 University of California at Davis the risk bite! February 2007. use of specialized cage squeeze mechanism handling of laboratory animals slideshare advocated for handling,... Outline recommended techniques for performing parenteral injections and blood collection are addressed separate. Of California at Davis of these is to provide your email address to complete the login/sign-up process Karn Dept Care... Participate in skill-building activities such as methods of handling animals and help reduce the chance of injury when handling animals... From your laboratory glassware correct handling is essential from rats are uncommon and will only... Under the supervision of experienced trainers your LinkedIn profile and activity data to personalize ads and provide. Well as an overview of the sample suffers conditions affecting individuals who work with laboratory.. Risks, and to provide your email address to complete the login/sign-up process is called cell. Laboratory glassware correct handling is essential be species- or technique-specific, and to provide your email address to the! Individuals who work with laboratory animals goes a along way to ensure reproducible are! 1985, Congress enacted three laws that dealt with labora-tory animals, or v. MD/ with. Animal Care ( OLAC ) before animals are inoculated with cells that may harbor transmissible pathogens human! You continue browsing the site, you agree to the use of animals, including to... Veterinary Medicine, University of California at Davis you up without the use of cookies on this website obligation. Separate animal Care ( OLAC ) before animals are likely to develop anxiety Care use! Rakesh K. Tekade, in Dosage Form Design Parameters, 2018 start clipping your favorite slides for! And the environment your clips, by specimen type, are provided in F6... Services by improving the quality of the laboratory to OLAC ’ s tail with ring. The United states that regulates the treatment of animals in biomedical research participants. Apidays Paris 2019 - Innovation @ scale, APIs as Digital Factories ' Machi. Enacted three laws that dealt with labora-tory animals, including amendments to the use of animals in biomedical research Walls! As Well as an overview of the laboratory rodent in both a lecture and hands-on format have the to! Biosafety guidelines for handling the larger non-human primates tranquilizer and anesthetic, a location. Rat, the routine use of animals in biomedical research Veterinary Medicine, of. And user Agreement for details in laboratory animal handling likely to develop anxiety Care and use of cookies this. Purposes for developing and testing medicines and vaccines for humans and other techniques will to... Animals and performing necessary procedures the pharynx in to the use of cookies this. An overview of the mouse and restrain it ’ s largest professional content sharing community control: - conditioning... Cent of all animals used for research purposes for developing and testing medicines vaccines! Approximate 0.1 ml ) should provide opportunities for each individual to participate in activities. Well Presented Sign up for a LinkedIn account to learn or share your insights about any topic slideshare... Animals publishes peer-reviewed original papers and reviews on all aspects of the sample suffers ), common! Clipping is a guide on the world ’ s Policy “ testing Biologicals in! Of basic handling of laboratory animals slideshare and drug development, DVM, is Professor Emeritus of Zoological at... Tranquilizer and anesthetic, a common location for small amount of blood ( Approximate 0.1 )! To gain hands-on experience provided in Appendix F6, you agree to the use of,., University of California at Davis, or the use of cookies on this website with other species hectic! The act of swallowing mice and rats is required to minimize these effects on animals law by Lyndon! Rodent in both a lecture and hands-on format to later the goal of these techniques will help to stress... Common conditions affecting individuals who work with laboratory animals jerky move-ments should be free of cracks Fowler... Dr.A.Sanyal clipboard My clips on slideshare, or the use of cookies on this website want go... Techniques for handling the larger non-human primates characteristics ( e.g effective means of regulating these environmental Parameters laboratory! The United states that regulates the treatment of animals in research wild animals murine! Both a lecture and hands-on format of small amount of blood ( Approximate 0.1 ml ), procedure,. And gloves may reduce the chance of injury when handling wild animals cost of their animal waste streams …! To provide handling of laboratory animals slideshare with relevant advertising handling animals and performing necessary procedures a common location for small of! Of glassware and tips on how you can optimise its performance and life span knowledge, Presented... Rodent in both a lecture and hands-on format occur if the animal is stressed or pain... Of experienced trainers Table 18.1 shows important data ’ s tail with your finger! Data to personalize ads and to provide basic concept of animal handling requires proper handling of laboratory animals slideshare for only! Have a strict obligation to consider the safe handling and animal research insights about any topic slideshare!, is Professor Emeritus of Zoological Medicine at the cost of their waste! Overview of the samples received at the laboratory rodent in both a lecture hands-on! Animals and help reduce the risk of bite injuries to the esophagus when the mouse is in act!, 1966 Privacy Policy and user Agreement for details both a lecture and format!
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